Sound issues with OpenShot running in Windows 10 are challenging to troubleshoot. Wrong settings may cause several sound issues under Windows. It can prevent hearing sound during playback in the interface, during encoding, or even mute sound in third-party programs while OpenShot is open. I took the following suggestions from the discussion in https://github.com/OpenShot/openshot-qt/issues/3116.

  1. Try resetting OpenShot to its default settings. Open File Explorer, browse to the C:\Users\(USERNAME)\.openshot_qt folder and delete it. Removing this folder removes settings and many things that can, in theory, become corrupt. OpenShot automatically recreates the folder with the default settings when relaunching the program.  The uninstaller does not delete the folder when the program is uninstalled, so your previous settings are saved, often causing projects to fail.
  2. Ensure that OpenShot's Playback Audio Device is set correctly for your sound interface/output under Preferences in the Preview tab. (Speakers vs. headphones, line out vs. USB vs. Bluetooth, etc.) Since it is a setting, you will need to restart OpenShot. Perhaps try a different audio device (USB, audio over HDMI from the video card, etc.) to rule out other clip audio issues.
  3. Check that the Default Audio Sample Rate and Default Audio Channels on the Preview tab of the Preferences window match your hardware. 
    Windows » Sound Control Panel »  Playback devices »  the_device_name »  Properties »  Advanced tab
  4. Disable automatic sound suppression for voice calls during microphone activity in the Windows Sound Control Panel. 
    Windows »  Sound Control Panel »  Playback devices »  the_device_name »  Properties »  Communications »  Do nothing
  5. Try disabling 'Audio Enhancements' under the advanced settings tab of your audio device in the Windows Sound Control Panel.
  6. Regarding headphones, plug in the headphones and then start OpenShot afterward. https://github.com/OpenShot/openshot-qt/issues/2565 
  7. Ensure that you have the latest security updates from Microsoft.  You may have to use the Windows 10 Update Assistant to update your Windows 10 to the latest security patches.
  8. Ensure that your device drivers are the latest WHQL certified versions.  You can download and install a free software driver update tool to check your device drivers and download updated versions if needed.
  9. Download and install the latest Daily Build from our website.  Before installing the Daily Build, the best approach is to uninstall OpenShot from the Control Panel or the Apps panel in Settings (in Windows).  After uninstalling OpenShot, delete the C:\Program Files\OpenShot Video Editor and C:\Users\(USERNAME)\.openshot_qt folders.  After deleting the folders, install the latest Daily Build and launch the program.